个人简介
高艺恬 女，1989年9月，博士，青年硕士生导师。2007年至2014年就读于沈阳药科大学，获得学士和硕士学位，2017年9月毕业于英国贝尔法斯特女王大学（药学），获得博士学位。目前研究方向：天然及基于靶点设计的活性多肽的抗菌及抗炎活性和机制研究。
主要研究领域
1.天然抗菌肽的发现及改造。
2.肽类药物的研究与开发
研究经历
2014.09–2017.07
博士（药物生物技术）英国贝尔法斯特女王大学，药学院
2011.09–2014.06
硕士（药物分析）沈阳药科大学，药学院
导师：赵春杰教授
2007.09–2011.07
学士（药学）沈阳药科大学，药学院
代表性荣誉
1.英国贝尔法斯特女王大学优秀博士奖学金，2015，2016
2.温州市海外精英引进计划-创新长期项目人才，2018
3.浙江省高校青年优秀人才培养计划，2020
主持国家级课题
靶向优化的新型抗菌肽ms-pt1a抗耐甲氧西林金黄色葡萄球菌的作用与机制研究，资助类别：青年科学基金项目，81803590，主持，在研。2019.01,01-2021.12.31，21万
发表论文
1.song, x., pan, h., wang, h., liao, x., sun, d., xu, k., chen, t., zhang, x., wu m., wu, d., gao, y. (2020)identification of new dermaseptins with self-assembly tendency: membrane disruption, biofilm eradication, and infected wound healing efficacy. acta biomaterialia, 6642. (if=7.242)
2.wu, d., gao, t., tan, y., liu, y., wang, l., zhou. m., xi. x., ma, c., olaf, r.p., chen, t., chaw, c.., (2018) discovery of distinctin-like-peptide-ph (dlp-ph) from the skin secretion of phyllomedusa hypochondrialis, a prototype of a novel family of antimicrobial peptide. frontiers in microbiology, 9:541. (if=4.076)
3.gao, y., wu, d., wang, l., chen, l., ma, c., xi, x., zhou, m., duan, j., olaf, r, p., chen, t. and shaw, c., (2017) targeted modification of a novel amphibian antimicrobial peptide from phyllomedusa tarsius to enhance its activity against mrsa and microbial biofilm. frontiers in microbiology 8: 628 (if=4.076).
4.gao, y., wu, d., xi, x., wu, y., ma, c., zhou, m., wang, l., yang, m., chen, t. and shaw, c., (2016) identification and characterisation of the antimicrobial peptide, phylloseptin-pt, from the skin secretion of phyllomedusa tarsius, and comparison of activity with designed, cationicityenhanced analogues and diastereomers. molecules, 21: 1667 (if=2.861).
5.wu, d.,gao, y., wang, l., xi, x., wu, y., zhou, m., zhang, y., ma, c., chen, t. and shaw, c., (2016), a combined molecular cloning and mass spectrometric method to identify, characterize, and design frenatin peptides from the skin secretion of litoria infrafrenata. molecules, 21:1429. (equal contribution, if=2.861).
6.shi, d., hou, x., wang, l.,gao, y., wu, d., xi, x., zhou, m., kwok, h., duan, j., chen, t. et al.,(2016), two novel dermaseptin-like antimicrobial peptides with anticancer activities from the skin secretion of pachymedusa dacnicolor.toxins.8: 144 (if=3.030).
7.shi, d., xi, x., wang, l.,gao, y., ma, c., chen, h., zhou, m., chen, t. and shaw, c., (2016), baltikinin: a new yyotropic tryptophyllin-3 peptide isolated from the skin secretion of the purple-sided leaf frog, phyllomedusa baltea.toxins.8: 213 (if=3.030).
8.yang, n., li, l., wu, d., gao, y., xi, x., zhou, m., wang, l., chen, t. and shaw, c., (2016) discovery of novel bacterial cell-penetrating phylloseptins in defensive skin secretions of the south american hylid frogs, phyllomedusa duellmani and phyllomedusa coelestis. toxins. 8: 255 (if=3.030).
9.gao, y.,zhao, l., sheng, m., wang, m., zhao, c., (2014) determination of the contents of four7 fatty acids in soybean oil for injection by gc-ms and gc. journal of shenyang pharmaceuticaluniversity, 30 (9): 704-708.
10.gao, y., zhao, l., sheng, m., wang, m., zhao, c., (2014) studying on the compatibility of soybean oil for injection and high density polyethylene bottles.west china journal of pharmaceutical sciences. 29 (2): 164-166.
11.sheng, m., zhao, l., gao, y., wang, m., zhao, c., (2014) compatibility of medium-chain triglycerides and hdpe bottles. journal of shenyang pharmaceutical university. 30 (3): 211-216.
12.sheng, m., zhao, l., gao, y., wang, m., zhao, c., (2014) identification and determination of medium- chain triglycerides. west china journal of pharmaceutical sciences. 29 (3): 323-325.
13.lin, q., cao, y,. gao, y., shen, c., zhao, c., (2012) determination of four kind of metal elements pernyi (hua) diels by faas. chinese journal of spectroscopy laboratory. 29 (6): 3609-3613.
14.lin, q., li, j.,gao, y., cao, y., (2011) method comparison of the determination of caffeine in tankejing powder. chinese journal of ethnomedicine and ethnopharmacy. 3:37-38
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