个人简介
孙达 男,博士&硕导(生物学学硕 & 药学专硕 两个专业方向招生)&生命科学研究院院长助理。本硕博均在重庆大学完成学业,期间(2014-2015)于中国科学院金属研究所联合培养一年。现主持科学研究项目4项,累计经费62万,并作为主要人员参与6项科学研究项目。在theranostics、materials science & engineering c、materials letters、 environmental science and pollution research等国内外学术刊物上发表论文26篇(累计if>80),其中第一/通讯作者论文15篇(累计if=52.918),获授权专利7项,转化1项。担任theranostics、science of the total environment、obesity、recent patents on anti-cancer drug discovery、archives of medical science等多个国际期刊审稿专家。
主要研究方向
医用材料的生物学功能化、新型药物递送系统的设计与开发、及生物资源开发与利用。
代表性论文第一#/通讯*作者
2015年度
(1)d. sun#, shahzad m. babar#, m.li, et al., antimicrobial materials with medical applications,materials technology, 2015.5.01, 30(b2): b90-b95
中科院4区,if=1.442
2016年度
(2)da sun#, dake xu#, chunguang yang,et al.,inhibition of staphylococcus aureus biofilm by a copper-bearing 317l-cu stainless steel and its corrosion resistance, materials science & engineering c-materials for biological applications, 2016.12.1, 69: 744-750
中科院2区,if=4.164
(3) da sun#, dake xu#, chunguang yang, et al., an investigation of the antibacterial ability and cytotoxicity of a novel cu-bearing 317l stainless steel, scientific reports, 2016.7.7, 29244
中科院2区,if=5.228
(4)da sun#,chuanren duan#,yaning shang, et al., application of faecalibacterium 16s rdna genetic marker for accurate identification of duck faeces, environmental science and pollution research, 2016.4.01, 23(8): 7639-7647
中科院3区,if=2.76
2017年度
(5)da sun#,kun zhang#,chuanren duan#*, et al.,potential application of an aspergillus strain in a pilot biofilter for benzene biodegradation, scientific reports, 2017.4.6, 46059
中科院2区,if=4.259
(6)wei wu#, jia chen#, da sun#*, et al., study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber. materialsletters, 2017.12.15, 209: 562-565
中科院2区,if=2.572
2018年度
(7)li luo#, wei wu#, da sun#, et al.,acid-activated melittin for targeted and safe antitumor therapy, bioconjugate chemistry, 2018, 29(9): 2936-2944
中科院2区,if=4.485
2019年度
(8)da sun#*, jia chen#, wei wu#, et al., mir‐802 causes nephropathy by suppressing nf‐κb‐repressing factor in obese mice and human, journal of cellular and molecular medicine, 2019.02.07, 23(4): 2863-2871
中科院2区,if=4.658
(9)d. sun*, j. chen, h. hu, et al., acanthopanax senticosus polysaccharide suppressing proliferation and metastasis of the human non-small cell lung cancer nci-h520 cells is associated with wnt/β-catenin signaling, neoplasma, 2019.7.29, 66(4): 555-563
中科院4区,if=1.771
(10)libo jin#, j. chen#, ..., da sun*,tripterygium wilfordii polyglycosides inhibittgf-beta 1/nf-kappa b signaling pathway and improve renal fibrosis in diabetic nephropathy, acta medica mediterranea, 2019.2.20, 35: 2787-2791
中科院4区,if=0.835
(11)da sun#, jia chen#, ..., libo jin*, wei wu*, advances in refunctionalization of erythrocyte-based nanomedicine for enhancing cancer-targeted drug delivery, theranostics, 2019.9.21, 9(23): 6885-6900
中科院1区,if=8.063
2020年度
(12) renyi peng#,hao ji#, libo jin#, ..., da sun*, wei wu#, et al., macrophage-based therapies for atherosclerosis management, journal of immunology research, 2020.01, 8131754
中科院3区,if=3.404
(13) kun zhang#, da sun#*, chuanren duan#*, et al., application of a faecalibacterium 16s rdna genetic marker for species identification of dog fecal waste, environmental science and pollution research, 2020.5.29,online.
中科院3区,if=2.914
(14) guoming zeng, maolan zhang, pei gao, jiale wang, da sun*, algicidal efficiency and genotoxic effects of phanerochaete chrysosporium against microcystis aeruginosa,international journal of environmental research and public health, 2020.5.30,17(11): 4029
中科院4区,if=2.468 https://doi.org/10.3390/ijerph17114029
(15)guoming zeng, pei gao, jiale wang, jinxi zhang, maolan zhang*, da sun*, molecular algicidal mechanism and toxicological degradation of microcystis aeruginosa by white rot fungi,toxins, 2020.6.18,12(6): 406
中科院3区,if=3.895 https://doi.org/10.3390/toxins12060406
非第一/通讯作者论文
(1) 成功桥饮用水水库污染特征分析及对策探讨,2011年环境污染与大众健康学术会议,2011.09.30,1106–1109, 1/8;
(2) 白腐菌木质素降解酶及其在木质素降解过程中的相互作用,生物技术通报,2011.10.26,(10):32–36, 4/5;
(3) 1株甲苯降解真菌的筛选鉴定及其降解甲苯的特性,微生物学杂志,2011.5.15, (03):41~47, 6/6;
(4) 应用faecalibacterium菌示踪水环境粪便污染研究进展,应用与环境生物学报,2013.12.25, (06):1073–1078, 7/8;
(5) laboratory investigation of the microbiologically influenced corrosion (mic) resistance of a novel cu-bearing 2205 duplex stainless steel in the presence of an aerobic marine pseudomonas aeruginosa biofilm,biofouling,2015.01.01,31(6):481–492, 4/9;
(6) evaluation of faecalibacterium 16s rdna genetic markers for accurate identification of swine faecal waste by quantitative pcr,journal of environmental management,2016.10.1,181:193–200, 7/8;
(7) 基于专利数据的血管内支架研究发展趋势分析,北京生物医学工程,2017.06.16, (03): 290–297, 4/8;
(8) shear stress-mediated angiogenesis through id1 relevant to atherosclerosis, molecular & cellular biomechanics, 2017, 14(2): 83–100, 9/12;
(9) dual tumor-targeted poly(lactic-co-glycolic acid)–polyethylene glycol–folic acid nanoparticles: a novel biodegradable nanocarrier for secure and efficient antitumor drug delivery,international journal of nanomedicine,2017.7.18,12:5745–5760, 7/10;
(10) genotoxicity effects of phanerochaete chrysosporium against harmful algal bloom species by micronucleus test and comet assay,chemosphere,2018.11.24,218:1031–1041, 6/6;
(11) antibacterial durability and biocompatibility of antibacterial-passivated 316l stainless steel in simulated physiological environment,materials science & engineering c-materials for biological applications,2019.3.8,100:396–410, 3/8;
(12) comprehensive analysis of ogura cytoplasmic male sterility-related genes in turnip (brassica rapa ssp. rapifera) using rna sequencing analysis and bioinformatics, plos one,2019.6.14,14(6):e0218029, 6/9;
(13) interleukin‐1β augments the angiogenesis of endothelial progenitor cells in an nf‐κb/cxcr7‐dependent manner, journal of cellular and molecular medicine,2020.4.2, 8/16;
(14) identification of new dermaseptins with self-assembly tendency: membrane disruption, biofilm eradication, and infected wound healing efficacy, acta biomaterialia,2020.4.9, 5/11.
授权专利
(1) 孙达,等,一种生物滤塔,实用新型,zl201220018146.5;
(2) 段传人,崔亚敏,张坤,孙达,等,一种含有pfb-1引物对的猪粪便污染检测试剂盒及其制备与应用,发明专利,zl201610036898.7;(已转化,)
(3) 段传人,崔亚敏,张坤,孙达,等,一种含有pfb-2引物对的猪粪便污染检测试剂盒及其制备与应用,发明专利,zl201610037363.1;
(4) 孙达,等,一种实验用白腐真菌控藻装置,实用新型,zl201821574235.1;
(5) 孙达,等,试管清洗装置,实用新型,zl201822114229.4;
(6) 金立波,孙达,等,康复行走训练医用拐杖,实用新型,zl201822169717.5;
(7) 金立波,尹海燕,孙达,等,一种新型医学检验管,实用新型,zl201821596956.2。
主持课题:
(1) 浙江省药学重中之重一级学科开放基金,201720,2017-2019,6万;
(2) 温州市水污染控制与治理科技创新项目,w20170010,2017-2020,20万;
(3) 浙江省自然科学基金青年项目,q19e010021,2019-2021,10万;
(4) 国家自然科学基金青年项目,51901160,2020-2022,26万。
参与课题
(1) 2014/01-2017/12,国家自然科学基金面上项目,31370949,高切应力促进血管新生介导易损斑块形成的力生物学机制,82万,6/10;
(2) 2017/01-2019/12,国家自然科学基金青年项目,51603023,血小板膜包被仿生纳米前药用于高效靶向抑制血管再狭窄的研究,20万,2/6;
(3) 2017/08-2018/12,温州市科技计划项目,2017n0015,一氧化氮(no)提升水涝灾害后玉米幼苗成活率的研究,3万,3/6;
(4) 2019/01-2020/12,温州市科技计划项目,2018g0178,多耐受酵母pichia kudriavzevii低ph发酵生产d-木糖酸的关键技术研究,5万,3/5;
(5) 2019/01-2021/12,国家自然科学基金青年项目,81803590,靶向优化的新型抗菌肽ms-pt1a抗耐甲氧西林金黄色葡萄球菌的作用与机制研究,21万,4/7;
(6) 2020/01-2023/12,国家自然科学基金面上项目,31972418,白菜花粉响应低温胁迫的lncrna-brcbf4-cor基因调控通路研究,58万,5/10.
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